Across TCGA patient cohorts, SPATA12 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,158 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SPATA12-associated GO terms across cancer lineages are Cellular response to oxidative stress, Positive regulation of DNA metabolic process, and Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process. Each is linked with SPATA12 in more than 20 cancer types. Because this analysis shows association rather than direction, both SPATA12-to-partner and partner-to-SPATA12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPATA12→partner) and Y-score (partner→SPATA12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Cellular response to oxidative stress →	+0.057	+0.298	<.001	.002	3	21
STAD	Positive regulation of DNA metabolic process →	+0.036	+0.213	<.001	<.001	3	19
KICH	Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process →	+0.046	+0.217	<.001	.002	3	19
STAD	Negative regulation of mitotic cell cycle →	+0.039	+0.243	<.001	<.001	3	19
SCLC	Response to sterol depletion →	+0.144	+0.294	<.001	<.001	3	19
SCLC	Regulation of viral process →	+0.164	+0.402	<.001	<.001	2	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,158 associations by consensus.

Exploration

SPATA12 survival (RNA) · tumor vs normal (RNA) · all SPATA12 data types