SPART

Across TCGA patient cohorts, SPART protein abundance is significantly associated with the RNA expression of many other genes, with 8,644 significant associations in total. COAD shows the largest number of these associations.

The most reproducible SPART-associated genes across cancer lineages are KATNAL1, RASL12, and GNG11. Each is linked with SPART in more than 5 cancer types. Because this analysis shows association rather than direction, both SPART-to-partner and partner-to-SPART results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPART versus KATNAL1 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPART→partner) and Y-score (partner→SPART) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KATNAL1 →	+0.735	+0.487	<.001	.002	3	5
UCEC	RASL12 →	+0.899	+0.422	<.001	<.001	3	5
UCEC	GNG11 →	+0.918	+0.286	<.001	.003	3	5
UCEC	PHYHIP →	+0.560	+0.317	<.001	.001	3	5
UCEC	LRRN4CL →	+0.877	+0.328	<.001	<.001	3	5
UCEC	APOD →	+1.657	+0.428	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,644 associations by consensus.

SPART vs KATNAL1 — UCEC

Explore this scatter interactively →