SPART

Across TCGA cell cohorts, SPART RNA expression is significantly associated with the go_rna of many other GO terms, with 4,617 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SPART-associated GO terms across cancer lineages are Establishment of epithelial cell apical/basal polarity, Lipophagy, and Transcription preinitiation complex assembly. Each is linked with SPART in more than 7 cancer types. Because this analysis shows association rather than direction, both SPART-to-partner and partner-to-SPART results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of epithelial cell apical/basal polarity grouped by SPART-low versus SPART-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPART→partner) and Y-score (partner→SPART) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Establishment of epithelial cell apical/basal polarity →	+0.136	+1.342	<.001	.001	3	8
BLOOD_Myeloma	Lipophagy →	-0.204	-2.714	<.001	<.001	3	8
STOMACH	Transcription preinitiation complex assembly →	+0.068	+2.560	.001	.001	3	7
SOFT_TISSUE	Nuclear membrane organization →	+0.072	+1.996	<.001	<.001	2	8
LUNG_NSCLC_LUAD	Immunological synapse formation →	+0.165	+1.180	.007	.008	3	7
BONE	Paranodal junction assembly →	-0.637	-0.874	.005	.004	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,617 associations by consensus.

Establishment of epithelial cell apical/basal polarity by SPART expression — BREAST

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