SPANXN1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPANXN1 mutation is significantly associated with the RNA expression of many other genes, with 826 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPANXN1-associated genes across cancer lineages are RNU6-1233P, TNC, and ZIC2. Each is linked with SPANXN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPANXN1-to-partner and partner-to-SPANXN1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXN1→partner) and Y-score (partner→SPANXN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRNU6-1233P →+0.179+3.776<.001.00234
UCECTNC →+1.402+2.243<.001.00632
UCECZIC2 →+1.543+2.243.002.00632
HNSCRN7SL362P →+0.222+5.015<.001.00932
LUADRN7SKP112 →+0.167+3.868.002.00132
LUADOR7E110P →+0.168+3.658<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 826 associations by consensus.

Exploration