Across TCGA cell cohorts, SPANXC RNA expression is significantly associated with the go_rna of many other GO terms, with 1,125 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SPANXC-associated GO terms across cancer lineages are Cellular response to abiotic stimulus, Positive regulation of intracellular transport, and Cellular response to environmental stimulus. Each is linked with SPANXC in more than 5 cancer types. Because this analysis shows association rather than direction, both SPANXC-to-partner and partner-to-SPANXC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPANXC→partner) and Y-score (partner→SPANXC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Cellular response to abiotic stimulus →	+0.025	+0.271	.007	.008	3	6
BONE	Positive regulation of intracellular transport →	+0.071	+1.650	<.001	.003	3	6
LARGE_INTESTINE	Cellular response to environmental stimulus →	+0.025	+0.271	.007	.008	3	6
BONE	Cellular response to hepatocyte growth factor stimulus →	+0.211	+1.312	<.001	.004	3	5
BONE	Positive regulation of cellular response to hypoxia →	-1.012	-1.289	<.001	.005	3	5
BONE	Negative regulation of intrinsic apoptotic signaling pathway →	+0.090	+1.255	<.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,125 associations by consensus.

Exploration

SPANXC survival (RNA) · tumor vs normal (RNA) · all SPANXC data types