SPAG6

Across TCGA patient cohorts, SPAG6 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,950 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SPAG6-associated proteins across cancer lineages are PTER, CAPS, and REPS2. Each is linked with SPAG6 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPAG6-to-partner and partner-to-SPAG6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPAG6 versus PTER in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG6→partner) and Y-score (partner→SPAG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTER →	+0.853	+0.637	<.001	<.001	3	4
LSCC	CAPS →	+1.062	+0.861	<.001	<.001	3	4
GBM	REPS2 →	+0.536	+0.454	<.001	.002	3	3
GBM	SH3BGRL2 →	+0.730	+0.613	<.001	<.001	3	3
BRCA	IFT43 →	+0.266	+0.934	.005	.002	3	3
LUAD	IFT74 →	+0.298	+1.216	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,950 associations by consensus.

SPAG6 vs PTER — GBM

Explore this scatter interactively →