SPAG6

Across TCGA cell cohorts, SPAG6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,369 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SPAG6-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Positive regulation of immature T cell proliferation, and Positive regulation of immature T cell proliferation in thymus. Each is linked with SPAG6 in more than 6 cancer types. Because this analysis shows association rather than direction, both SPAG6-to-partner and partner-to-SPAG6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by SPAG6-low versus SPAG6-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG6→partner) and Y-score (partner→SPAG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of syncytium formation by plasma membrane fusion →	+0.067	+0.407	.001	.003	2	7
BLOOD_Leukemia	Positive regulation of immature T cell proliferation →	+0.418	+2.145	<.001	<.001	3	5
BLOOD_Leukemia	Positive regulation of immature T cell proliferation in thymus →	+0.418	+2.145	<.001	<.001	3	5
SOFT_TISSUE	Regulation of organelle assembly →	+0.040	+0.539	<.001	.001	3	5
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.068	+0.331	.003	.003	2	6
OESOPHAGUS	Regulation of intracellular protein transport →	+0.045	+0.073	.004	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,369 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by SPAG6 expression — BLOOD_Lymphoma

Explore this box plot interactively →