SPAG17

Across TCGA patient cohorts, SPAG17 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,803 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SPAG17-associated proteins across cancer lineages are WDR35, NPHP4_S142, and OSCP1. Each is linked with SPAG17 in more than 4 cancer types. Because this analysis shows association rather than direction, both SPAG17-to-partner and partner-to-SPAG17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPAG17 versus WDR35 in OV, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG17→partner) and Y-score (partner→SPAG17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WDR35 →	+0.474	+1.319	<.001	<.001	3	5
LSCC	NPHP4_S142 →	+0.521	+0.696	<.001	.004	3	4
OV	OSCP1 →	+0.470	+0.884	.001	.001	3	4
BRCA	IFT22 →	+0.254	+1.157	<.001	<.001	3	4
BRCA	KATNIP →	+0.251	+1.117	.004	<.001	3	4
BRCA	CRACDL_S881 →	+1.015	+1.425	.007	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,803 associations by consensus.

SPAG17 vs WDR35 — OV

Explore this scatter interactively →