SPAG16

Across TCGA patient cohorts, SPAG16 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,432 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SPAG16-associated proteins across cancer lineages are IFT88, RPL18A_S123, and BBS7. Each is linked with SPAG16 in more than 5 cancer types. Because this analysis shows association rather than direction, both SPAG16-to-partner and partner-to-SPAG16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPAG16 versus IFT88 in UCEC, with a Pearson correlation of 0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG16→partner) and Y-score (partner→SPAG16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IFT88 →	+0.342	+0.740	<.001	.008	3	6
GBM	RPL18A_S123 →	-0.573	-0.335	<.001	.001	3	5
UCEC	BBS7 →	+0.297	+0.945	.004	<.001	3	5
GBM	WDR19 →	+0.347	+0.543	<.001	<.001	3	5
LUAD	DDAH1 →	+0.517	+0.495	.001	<.001	3	5
UCEC	DYNC2H1 →	+0.494	+1.095	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,432 associations by consensus.

SPAG16 vs IFT88 — UCEC

Explore this scatter interactively →