SPAG16

Across TCGA cell cohorts, SPAG16 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,907 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPAG16-associated GO terms across cancer lineages are Transport along microtubule, Intraciliary transport, and Vesicle coating. Each is linked with SPAG16 in more than 9 cancer types. Because this analysis shows association rather than direction, both SPAG16-to-partner and partner-to-SPAG16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transport along microtubule grouped by SPAG16-low versus SPAG16-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG16→partner) and Y-score (partner→SPAG16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Transport along microtubule →	+0.032	+1.514	<.001	<.001	3	10
BLOOD_Lymphoma	Intraciliary transport →	+0.044	+1.617	<.001	<.001	3	9
PANCREAS	Vesicle coating →	+0.087	+1.142	<.001	<.001	3	9
CNS	Intraciliary anterograde transport →	+0.072	+0.572	.004	.003	3	8
LUNG_NSCLC_LUAD	Protein localization to cilium →	+0.035	+0.529	.006	.006	2	9
LUNG_SCLC	Microtubule-based transport →	+0.054	+0.900	.002	.008	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,907 associations by consensus.

Transport along microtubule by SPAG16 expression — BLOOD_Leukemia

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