SPAG11A

Across TCGA patient cohorts, SPAG11A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,263 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPAG11A-associated GO terms across cancer lineages are Heterochromatin organization, Regulation of cyclin-dependent protein kinase activity, and Multi-multicellular organism process. Each is linked with SPAG11A in more than 6 cancer types. Because this analysis shows association rather than direction, both SPAG11A-to-partner and partner-to-SPAG11A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin organization grouped by SPAG11A-low versus SPAG11A-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG11A→partner) and Y-score (partner→SPAG11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Heterochromatin organization →	+0.065	+0.473	.004	<.001	3	7
SCLC	Regulation of cyclin-dependent protein kinase activity →	+0.082	+0.669	<.001	.005	3	6
STAD	Multi-multicellular organism process →	+0.040	+0.085	<.001	<.001	3	6
SCLC	Translocation of molecules into host →	+0.094	+0.637	<.001	.001	2	7
STAD	mRNA export from nucleus →	+0.072	+0.085	<.001	<.001	3	6
STAD	Cellular ketone metabolic process →	+0.040	+0.082	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,263 associations by consensus.

Heterochromatin organization by SPAG11A expression — SCLC

Explore this box plot interactively →