SPAG1

Across TCGA patient cohorts, SPAG1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,637 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPAG1-associated genes across cancer lineages are RNF19A, PHIP, and CEP192. Each is linked with SPAG1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SPAG1-to-partner and partner-to-SPAG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPAG1 versus RNF19A in GBM, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAG1→partner) and Y-score (partner→SPAG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RNF19A →	+0.988	+0.728	<.001	<.001	3	7
HNSC	PHIP →	-0.687	-0.472	<.001	<.001	3	5
HNSC	CEP192 →	-0.758	-0.589	<.001	<.001	3	4
BRCA	FAM20A →	-0.705	-0.382	<.001	<.001	3	4
UCEC	ADGB →	+1.248	+0.622	<.001	<.001	3	4
OV	RIDA →	+0.615	+0.478	<.001	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,637 associations by consensus.

SPAG1 vs RNF19A — GBM

Explore this scatter interactively →