SPACA7

Across TCGA patient cohorts, SPACA7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,280 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPACA7-associated GO terms across cancer lineages are ATP biosynthetic process, Response to carbohydrate, and Carbohydrate catabolic process. Each is linked with SPACA7 in more than 8 cancer types. Because this analysis shows association rather than direction, both SPACA7-to-partner and partner-to-SPACA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP biosynthetic process grouped by SPACA7-low versus SPACA7-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPACA7→partner) and Y-score (partner→SPACA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	ATP biosynthetic process →	+0.084	+0.113	<.001	<.001	3	9
STAD	Response to carbohydrate →	+0.054	+0.084	<.001	<.001	3	8
STAD	Carbohydrate catabolic process →	+0.069	+0.085	<.001	<.001	3	8
STAD	Regulation of lysosomal lumen pH →	+0.064	+0.115	<.001	<.001	3	8
STAD	Intrinsic apoptotic signaling pathway by p53 class mediator →	+0.071	+0.099	<.001	<.001	3	7
STAD	Proton transmembrane transport →	+0.064	+0.110	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,280 associations by consensus.

ATP biosynthetic process by SPACA7 expression — STAD

Explore this box plot interactively →