SPACA6P-AS

Across TCGA pan-cancer cohorts, SPACA6P-AS RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of SPACA6P-AS’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where SPACA6P-AS RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SPACA6P-AS is over-expressed in tumor.

BLCA, BRCA, and CHOL are the cancer types where SPACA6P-AS tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SPACA6P-AS RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.109	.005	8	view →
BRCA	All	II,III,IV	+0.187	<.001	6	view →
CHOL	All	All	+0.285	<.001	5	view →
LIHC	Female	All	+0.016	.001	4	view →
PAAD	Male	All	+0.245	.026	2	view →
THCA	All	All	+0.105	.023	1	view →
HNSC	Female	IV	+0.028	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

SPACA6P-AS–BLCA

Open the BLCA breakdown →