SPACA5B

Across TCGA patient cohorts, SPACA5B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SPACA5B-associated genes across cancer lineages are SNORD115-22 and PABPC1L2B-AS1. Each is linked with SPACA5B in more than 1 cancer types. Because this analysis shows association rather than direction, both SPACA5B-to-partner and partner-to-SPACA5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD115-22 grouped by SPACA5B-low versus SPACA5B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPACA5B→partner) and Y-score (partner→SPACA5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SNORD115-22 →	+0.383	+7.816	<.001	.008	3	1
SKCM	PABPC1L2B-AS1 →	+0.034	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SNORD115-22 by SPACA5B expression — SKCM

Explore this box plot interactively →