SPACA3

Across TCGA patient cohorts, SPACA3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,652 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SPACA3-associated proteins across cancer lineages are NAA35, ARHGAP5, and RAE1. Each is linked with SPACA3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SPACA3-to-partner and partner-to-SPACA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPACA3 versus NAA35 in LSCC, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPACA3→partner) and Y-score (partner→SPACA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NAA35 →	-0.241	-0.124	<.001	<.001	3	4
COAD	ARHGAP5 →	-0.209	-1.106	.001	<.001	3	3
COAD	RAE1 →	+0.195	+0.760	<.001	<.001	3	3
PDAC	CFTR →	+0.883	+0.515	<.001	<.001	3	3
COAD	DKC1 →	+0.336	+1.090	<.001	<.001	3	3
PDAC	PPP2R1A →	-0.164	-0.343	.007	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,652 associations by consensus.

SPACA3 vs NAA35 — LSCC

Explore this scatter interactively →