SPACA1

Across TCGA patient cohorts, SPACA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,540 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SPACA1-associated GO terms across cancer lineages are Mitochondrial gene expression, mRNA 3'-end processing, and DNA-templated transcription initiation. Each is linked with SPACA1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SPACA1-to-partner and partner-to-SPACA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial gene expression grouped by SPACA1-low versus SPACA1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SPACA1→partner) and Y-score (partner→SPACA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial gene expression →	+0.085	+0.068	<.001	<.001	3	9
STAD	mRNA 3'-end processing →	+0.071	+0.054	<.001	<.001	3	9
STAD	DNA-templated transcription initiation →	+0.077	+0.053	<.001	<.001	3	8
STAD	Transcription preinitiation complex assembly →	+0.077	+0.058	<.001	<.001	3	8
STAD	Ribosomal small subunit biogenesis →	+0.088	+0.054	<.001	<.001	3	8
STAD	RNA methylation →	+0.066	+0.061	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,540 associations by consensus.

Mitochondrial gene expression by SPACA1 expression — STAD

Explore this box plot interactively →