SPACA1

Across TCGA cell cohorts, SPACA1 RNA expression is significantly associated with the RNA expression of many other genes, with 423 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SPACA1-associated genes across cancer lineages are DAZ2, OR2A25, and METTL21C. Each is linked with SPACA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SPACA1-to-partner and partner-to-SPACA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPACA1 versus DAZ2 in LARGE_INTESTINE, with a Pearson correlation of 0.80.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPACA1→partner) and Y-score (partner→SPACA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DAZ2 →	+0.199	+0.024	<.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	OR2A25 →	+0.111	+0.009	<.001	.001	3	3
SKIN	METTL21C →	+0.059	+0.083	.008	.009	3	2
UPPER_AERODIGESTIVE_TRACT	OR11A1 →	+0.016	+0.034	<.001	<.001	3	2
BLOOD_Lymphoma	TMCO5A →	+0.078	+0.028	<.001	<.001	3	2
LARGE_INTESTINE	GPX6 →	+0.424	+0.012	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 423 associations by consensus.

SPACA1 vs DAZ2 — LARGE_INTESTINE

Explore this scatter interactively →