SPAAR

Across TCGA patient cohorts, SPAAR RNA expression is significantly associated with the protein abundance of many other proteins, with 8,282 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SPAAR-associated proteins across cancer lineages are NES, ACVRL1_S160, and NID1. Each is linked with SPAAR in more than 4 cancer types. Because this analysis shows association rather than direction, both SPAAR-to-partner and partner-to-SPAAR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPAAR versus NES in BRCA, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPAAR→partner) and Y-score (partner→SPAAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NES →	+0.394	+0.426	<.001	<.001	3	5
LSCC	ACVRL1_S160 →	+0.752	+0.364	<.001	<.001	3	4
CCRCC	NID1 →	+0.373	+0.651	<.001	<.001	3	4
BRCA	MCAM →	+0.535	+0.438	<.001	<.001	3	4
CCRCC	MMRN2 →	+0.608	+0.918	<.001	<.001	3	4
BRCA	SYNM →	+0.693	+0.460	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,282 associations by consensus.

SPAAR vs NES — BRCA

Explore this scatter interactively →