SPA17

Across TCGA patient cohorts, SPA17 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,434 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SPA17-associated proteins across cancer lineages are TPPP3, IFT46, and IFT74. Each is linked with SPA17 in more than 6 cancer types. Because this analysis shows association rather than direction, both SPA17-to-partner and partner-to-SPA17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SPA17 versus TPPP3 in UCEC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SPA17→partner) and Y-score (partner→SPA17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TPPP3 →	+1.198	+0.648	<.001	<.001	3	7
UCEC	IFT46 →	+0.417	+0.717	<.001	.002	3	6
GBM	IFT74 →	+0.456	+0.836	<.001	<.001	3	6
BRCA	IFT88 →	+0.452	+0.881	<.001	<.001	3	6
UCEC	TTC25_S542 →	+1.790	+1.080	<.001	<.001	3	5
OV	RNF214 →	+0.228	+0.639	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,434 associations by consensus.

SPA17 vs TPPP3 — UCEC

Explore this scatter interactively →