SPA17

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SPA17 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SPA17-associated genes across cancer lineages are MEP. Each is linked with SPA17 in more than 1 cancer types. Because this analysis shows association rather than direction, both SPA17-to-partner and partner-to-SPA17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEP grouped by SPA17-low versus SPA17-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SPA17→partner) and Y-score (partner→SPA17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMEP →+0.037+3.180.014.01031
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MEP by SPA17 expression — UCEC

Box plot of MEP in SPA17-low vs SPA17-high samples in UCEC.

Explore this box plot interactively →

Exploration