Across TCGA patient cohorts, SP9 protein abundance is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SP9-associated genes across cancer lineages are DDX58, SGCA, and CACNG6. Each is linked with SP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SP9-to-partner and partner-to-SP9 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SP9→partner) and Y-score (partner→SP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DDX58 →	-2.276	-0.603	.002	<.001	3	1
GBM	SGCA →	-1.863	-0.636	.001	<.001	3	1
GBM	CACNG6 →	-1.453	-0.606	.003	<.001	3	1
GBM	HEG1 →	-0.919	-0.626	.009	<.001	3	1
GBM	PODN →	-1.369	-0.636	.005	<.001	3	1
GBM	NXPH1 →	-3.386	-0.583	.001	<.001	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration

SP9 survival (RNA) · tumor vs normal (RNA) · all SP9 data types