Across TCGA pan-cancer cohorts, SP9 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated SP9 data layer.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher SP9 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SP9 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SCLC show a favorable association.
KIRP, ACC, and KIRC are the cancer types where SP9 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.