Across TCGA patient cohorts, SP9 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SP9-associated genes across cancer lineages are RNU6-1082P, RPL23AP84, and MIR4710. Each is linked with SP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SP9-to-partner and partner-to-SP9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SP9→partner) and Y-score (partner→SP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1082P →	+0.897	+5.551	<.001	.004	3	1
UCEC	RPL23AP84 →	+0.258	+5.771	<.001	.003	3	1
UCEC	MIR4710 →	+1.321	+5.031	<.001	.009	3	1
UCEC	MIR4422 →	+1.036	+5.420	<.001	.005	3	1
COAD	LCE1C →	+0.195	+4.831	.005	.003	3	1
COAD	RNU1-35P →	+1.027	+5.797	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

SP9 survival (RNA) · tumor vs normal (RNA) · all SP9 data types