SP8

Across TCGA patient cohorts, SP8 protein abundance is significantly associated with the RNA expression of many other genes, with 122 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SP8-associated genes across cancer lineages are SEC23A, GLRA2, and BMX. Each is linked with SP8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SP8-to-partner and partner-to-SP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SP8 versus SEC23A in GBM, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SP8→partner) and Y-score (partner→SP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEC23A →	-0.515	-1.036	.001	.001	3	1
GBM	GLRA2 →	-2.498	-0.933	.006	.004	3	1
GBM	BMX →	-0.338	-1.286	.008	.005	3	1
GBM	FNDC3A →	-0.648	-1.008	.001	.002	3	1
GBM	ARHGEF7 →	-0.772	-1.014	.002	.002	3	1
GBM	KPNA3 →	-0.515	-0.911	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 122 associations by consensus.

SP8 vs SEC23A — GBM

Explore this scatter interactively →