Across TCGA patient cohorts, SP5 protein abundance is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SP5-associated genes across cancer lineages are LIPH, C1orf116, and RNU6-633P. Each is linked with SP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SP5-to-partner and partner-to-SP5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SP5→partner) and Y-score (partner→SP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LIPH →	+1.923	+0.386	<.001	.004	3	1
UCEC	C1orf116 →	+1.709	+0.386	.003	.004	3	1
UCEC	RNU6-633P →	+2.443	+0.386	.003	.004	3	1
UCEC	ALG1L6P →	+1.140	+0.386	.003	.004	3	1
UCEC	SNORD121B →	-1.566	-0.407	<.001	.007	3	1
UCEC	LINC02188 →	+0.883	+0.383	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

SP5 survival (RNA) · tumor vs normal (RNA) · all SP5 data types