SOX9

Across TCGA patient cohorts, SOX9 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,745 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SOX9-associated proteins across cancer lineages are CPM, NUP155, and PHF6. Each is linked with SOX9 in more than 4 cancer types. Because this analysis shows association rather than direction, both SOX9-to-partner and partner-to-SOX9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOX9 versus CPM in GBM, with a Pearson correlation of -0.46.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX9→partner) and Y-score (partner→SOX9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CPM →	-1.008	-0.848	<.001	<.001	3	5
GBM	NUP155 →	+0.162	+0.413	<.001	<.001	3	4
BRCA	PHF6 →	+0.382	+0.738	.001	<.001	3	4
GBM	FMNL1 →	-0.630	-0.634	<.001	<.001	3	4
UCEC	SOX9_S199 →	+1.385	+0.941	<.001	<.001	3	4
GBM	SRRT →	+0.357	+0.729	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,745 associations by consensus.

SOX9 vs CPM — GBM

Explore this scatter interactively →