SOX6

Across TCGA patient cohorts, SOX6 protein abundance is significantly associated with the protein abundance of many other proteins, with 11,992 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SOX6-associated proteins across cancer lineages are SOX6_S411, SOX6_S454, and SOX6_S466. Each is linked with SOX6 in more than 4 cancer types. Because this analysis shows association rather than direction, both SOX6-to-partner and partner-to-SOX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOX6 versus SOX6_S411 in BRCA, with a Pearson correlation of 0.87.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX6→partner) and Y-score (partner→SOX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SOX6_S411 →	+1.979	+1.610	<.001	<.001	3	5
LSCC	SOX6_S454 →	+2.224	+1.379	<.001	<.001	3	5
LSCC	SOX6_S466 →	+1.153	+1.339	<.001	<.001	3	4
UCEC	PRRC2C_T2675 →	+0.647	+0.540	<.001	<.001	3	3
GBM	ACTR2_T117 →	-0.735	-0.763	<.001	<.001	3	3
GBM	FHOD1 →	-0.429	-0.614	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,992 associations by consensus.

SOX6 vs SOX6_S411 — BRCA

Explore this scatter interactively →