SOX6

Across TCGA cell cohorts, SOX6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,634 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SOX6-associated GO terms across cancer lineages are ATP biosynthetic process, Regulation of syncytium formation by plasma membrane fusion, and Cytoplasmic translation. Each is linked with SOX6 in more than 10 cancer types. Because this analysis shows association rather than direction, both SOX6-to-partner and partner-to-SOX6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP biosynthetic process grouped by SOX6-low versus SOX6-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX6→partner) and Y-score (partner→SOX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	ATP biosynthetic process →	+0.093	+0.515	.003	.004	3	11
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.083	+0.901	.005	.004	3	10
SOFT_TISSUE	Cytoplasmic translation →	+0.071	+1.288	<.001	<.001	3	10
OVARY	Macroautophagy →	+0.048	+0.767	<.001	.009	3	9
LARGE_INTESTINE	Regulation of organelle assembly →	+0.020	+0.559	.007	.003	3	9
OESOPHAGUS	Negative regulation of mRNA catabolic process →	+0.087	+0.808	.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,634 associations by consensus.

ATP biosynthetic process by SOX6 expression — OESOPHAGUS

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