SOX21

Across TCGA patient cohorts, SOX21 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,790 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SOX21-associated proteins across cancer lineages are FAM114A2, FHOD1, and FMNL1. Each is linked with SOX21 in more than 3 cancer types. Because this analysis shows association rather than direction, both SOX21-to-partner and partner-to-SOX21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOX21 versus FAM114A2 in HNSC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX21→partner) and Y-score (partner→SOX21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FAM114A2 →	-0.316	-1.777	<.001	<.001	3	4
GBM	FHOD1 →	-0.381	-0.770	<.001	<.001	3	4
GBM	FMNL1 →	-0.500	-0.639	<.001	.009	3	4
GBM	MVP →	-0.560	-0.846	<.001	<.001	3	4
HNSC	MYH14 →	+0.823	+1.644	<.001	<.001	3	4
GBM	PIK3CD →	-0.554	-1.026	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,790 associations by consensus.

SOX21 vs FAM114A2 — HNSC

Explore this scatter interactively →