SOX17

Across TCGA cell cohorts, SOX17 RNA expression is significantly associated with the go_rna of many other GO terms, with 673 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SOX17-associated GO terms across cancer lineages are Regulation of centrosome cycle, Antimicrobial peptide production, and Antimicrobial peptide biosynthetic process. Each is linked with SOX17 in more than 2 cancer types. Because this analysis shows association rather than direction, both SOX17-to-partner and partner-to-SOX17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centrosome cycle grouped by SOX17-low versus SOX17-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX17→partner) and Y-score (partner→SOX17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of centrosome cycle →	+0.044	+0.175	.001	.006	3	3
OVARY	Antimicrobial peptide production →	+0.874	+2.711	.007	<.001	3	3
OVARY	Antimicrobial peptide biosynthetic process →	+0.874	+2.711	.007	<.001	3	3
OVARY	Antibacterial peptide production →	+0.874	+2.711	.007	<.001	3	3
OVARY	Antibacterial peptide biosynthetic process →	+0.874	+2.711	.007	<.001	3	3
OVARY	Proximal/distal pattern formation involved in nephron development →	-0.797	-2.637	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 673 associations by consensus.

Regulation of centrosome cycle by SOX17 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →