SOX15

Across TCGA patient cohorts, SOX15 protein abundance is significantly associated with the protein abundance of many other proteins, with 19,306 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SOX15-associated proteins across cancer lineages are ARID5A_S463, ARRB1, and ARRB1_S412. Each is linked with SOX15 in more than 1 cancer types. Because this analysis shows association rather than direction, both SOX15-to-partner and partner-to-SOX15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOX15 versus ARID5A_S463 in LSCC, with a Pearson correlation of -0.43.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX15→partner) and Y-score (partner→SOX15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARID5A_S463 →	-0.620	-1.074	<.001	<.001	3	2
HNSC	ARRB1 →	-0.419	-0.623	<.001	.001	3	2
HNSC	ARRB1_S412 →	-0.612	-0.769	<.001	<.001	3	2
HNSC	ATM →	-0.343	-0.650	.001	.002	3	2
LSCC	ACSL5 →	-0.518	-0.655	<.001	.001	3	2
LSCC	BAIAP2 →	+0.620	+0.896	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,306 associations by consensus.

SOX15 vs ARID5A_S463 — LSCC

Explore this scatter interactively →