SOX10

Across TCGA patient cohorts, SOX10 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,564 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SOX10-associated proteins across cancer lineages are S100B, PRKAR2B, and RPL5. Each is linked with SOX10 in more than 5 cancer types. Because this analysis shows association rather than direction, both SOX10-to-partner and partner-to-SOX10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOX10 versus S100B in LUAD, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX10→partner) and Y-score (partner→SOX10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	S100B →	+1.008	+0.219	<.001	<.001	3	6
GBM	PRKAR2B →	+0.580	+1.587	<.001	<.001	3	5
GBM	RPL5 →	-0.223	-1.626	<.001	<.001	3	5
COAD	PPP1R12B →	+0.839	+0.283	<.001	.009	3	4
HNSC	S100A9 →	-0.803	-0.852	<.001	.001	3	4
BRCA	SFRP1 →	+1.167	+1.885	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,564 associations by consensus.

SOX10 vs S100B — LUAD

Explore this scatter interactively →