Across TCGA patient cohorts, SOX1 protein abundance is significantly associated with the RNA expression of many other genes, with 230 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SOX1-associated genes across cancer lineages are FABP3, ZMYM5, and DMTF1. Each is linked with SOX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SOX1-to-partner and partner-to-SOX1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOX1→partner) and Y-score (partner→SOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FABP3 →	+2.161	+2.366	<.001	<.001	3	1
BRCA	ZMYM5 →	+0.314	+1.828	.007	<.001	3	1
BRCA	DMTF1 →	+0.661	+2.307	.001	<.001	3	1
BRCA	MIR26B →	+1.480	+2.307	<.001	<.001	3	1
BRCA	SNORA30 →	+1.045	+2.241	<.001	<.001	3	1
BRCA	RNA5SP467 →	+1.286	+1.828	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 230 associations by consensus.

Exploration

SOX1 survival (RNA) · tumor vs normal (RNA) · all SOX1 data types