Across TCGA pan-cancer cohorts, SOWAHC Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SOWAHC data layer compared with 24 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SOWAHC Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SOWAHC expression acts as an unfavorable survival marker.

UCEC, PRAD, and ACC are the cancer types where SOWAHC Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →
BLCA	OS	Median	III,IV	0.228	0.684	.023	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: SOWAHC tumor-vs-normal RNA expression · all SOWAHC data types