SOWAHC

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SOWAHC mutation is significantly associated with the RNA expression of many other genes, with 3,061 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SOWAHC-associated genes across cancer lineages are MIR1305, LINC00458, and RN7SL97P. Each is linked with SOWAHC in more than 2 cancer types. Because this analysis shows association rather than direction, both SOWAHC-to-partner and partner-to-SOWAHC results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOWAHC→partner) and Y-score (partner→SOWAHC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCMIR1305 →+0.325+4.812<.001.00633
CESCLINC00458 →+0.126+4.653.006.00432
CESCRN7SL97P →+0.156+5.144<.001.00332
UCECMRPL37 →+0.490+2.874<.001<.00132
UCECCA14 →+0.556+2.627.002.00532
UCECCDCA8 →+0.653+2.823.003.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,061 associations by consensus.

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