Across TCGA cell cohorts, SOWAHC mutation is significantly associated with the drug of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SOWAHC-associated genes across cancer lineages are IWP-2, Entospletinib, and PRT062607. Each is linked with SOWAHC in more than 1 cancer types. Because this analysis shows association rather than direction, both SOWAHC-to-partner and partner-to-SOWAHC results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOWAHC→partner) and Y-score (partner→SOWAHC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IWP-2 →	+0.350	+2.893	.007	.034	3	1
LARGE_INTESTINE	Entospletinib →	+0.399	+2.646	.037	.047	3	1
LARGE_INTESTINE	PRT062607 →	+0.647	+2.769	.009	.040	3	1
LARGE_INTESTINE	LCL161 →	+0.372	+2.646	.022	.047	2	1
LARGE_INTESTINE	TAF1_5496 →	+0.716	+2.777	<.001	.038	2	1
LARGE_INTESTINE	Savolitinib →	+0.403	+2.777	.024	.038	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

SOWAHC survival (RNA) · tumor vs normal (RNA) · all SOWAHC data types