SOWAHB

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SOWAHB mutation is significantly associated with the RNA expression of many other genes, with 2,356 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SOWAHB-associated genes across cancer lineages are OR1D4, LINC01399, and MAPKAPK5P1. Each is linked with SOWAHB in more than 2 cancer types. Because this analysis shows association rather than direction, both SOWAHB-to-partner and partner-to-SOWAHB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOWAHB→partner) and Y-score (partner→SOWAHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMOR1D4 →+0.021+3.732<.001.00133
UCECLINC01399 →+0.175+1.771<.001.00233
LGGMAPKAPK5P1 →+0.038+6.632<.001.00132
LGGRN7SL87P →+0.163+5.266<.001.00632
LGGMIR8080 →+0.446+5.327<.001.00632
READRN7SL578P →+0.172+5.039<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,356 associations by consensus.

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