SOWAHA

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SOWAHA mutation is significantly associated with the RNA expression of many other genes, with 4,174 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SOWAHA-associated genes across cancer lineages are LINC01523, RNY4P27, and RNU6-879P. Each is linked with SOWAHA in more than 1 cancer types. Because this analysis shows association rather than direction, both SOWAHA-to-partner and partner-to-SOWAHA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOWAHA→partner) and Y-score (partner→SOWAHA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMLINC01523 →+0.356+5.208<.001.00132
UCECRNY4P27 →+0.156+3.206<.001.00132
UCECRNU6-879P →+0.348+1.944.002.00232
UCECRNA5SP492 →+0.203+2.022<.001.00632
BLCARNU6-586P →+0.593+7.640<.001.00931
BLCAMIR4276 →+0.336+7.640<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,174 associations by consensus.

Exploration