SORCS3

Across TCGA cell cohorts, SORCS3 RNA expression is significantly associated with the RNA expression of many other genes, with 566 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible SORCS3-associated genes across cancer lineages are SMCP, CLLU1-AS1, and HTR1B. Each is linked with SORCS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SORCS3-to-partner and partner-to-SORCS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SORCS3 versus SMCP in BLOOD_Leukemia, with a Pearson correlation of 0.82.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SORCS3→partner) and Y-score (partner→SORCS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SMCP →	+0.029	+0.062	<.001	<.001	3	2
BLOOD_Leukemia	CLLU1-AS1 →	+0.517	+0.023	.001	.008	3	2
BLOOD_Lymphoma	HTR1B →	+0.065	+0.264	<.001	.001	3	1
STOMACH	SMR3A →	+0.013	+0.128	.005	<.001	3	1
STOMACH	CHIT1 →	+0.105	+0.039	<.001	.002	3	1
STOMACH	ASB15 →	+0.021	+0.040	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 566 associations by consensus.

SORCS3 vs SMCP — BLOOD_Leukemia

Explore this scatter interactively →