SOD2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SOD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,229 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SOD2-associated proteins across cancer lineages are NADK, PARVG, and TNFAIP8. Each is linked with SOD2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SOD2-to-partner and partner-to-SOD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOD2 versus NADK in OV, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOD2→partner) and Y-score (partner→SOD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVNADK →+0.510+1.270<.001<.00139
GBMPARVG →+0.507+0.995<.001<.00139
GBMTNFAIP8 →+0.561+1.115<.001<.00139
OVTNFAIP8L2 →+0.752+1.072<.001<.00139
OVSPN →+1.062+1.196<.001<.00139
GBMHCK →+0.623+1.103<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 24,229 associations by consensus.

SOD2 vs NADK — OV

Per-sample scatter of SOD2 vs NADK in OV (Pearson r = 0.44).

Explore this scatter interactively →

Exploration