SOD1

Across TCGA cell cohorts, SOD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,054 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SOD1-associated GO terms across cancer lineages are Ketone metabolic process, Negative regulation of mitotic nuclear division, and DNA replication-dependent chromatin assembly. Each is linked with SOD1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SOD1-to-partner and partner-to-SOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ketone metabolic process grouped by SOD1-low versus SOD1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SOD1→partner) and Y-score (partner→SOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Ketone metabolic process →	+0.098	+0.584	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic nuclear division →	+0.148	+0.909	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	DNA replication-dependent chromatin assembly →	+0.149	+1.330	<.001	<.001	3	11
LUNG_SCLC	Vitamin K metabolic process →	+0.260	+0.643	<.001	<.001	3	11
LUNG_NSCLC_LUAD	ATP metabolic process →	+0.057	+0.741	.004	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of nuclear division →	+0.168	+1.260	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,054 associations by consensus.

Ketone metabolic process by SOD1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →