SOD1

Across TCGA cell cohorts, SOD1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,366 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SOD1-associated genes across cancer lineages are TRIO, RBKS, and TTLL12. Each is linked with SOD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SOD1-to-partner and partner-to-SOD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOD1 versus TRIO in BLOOD_Lymphoma, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOD1→partner) and Y-score (partner→SOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TRIO →	-1.821	-0.948	<.001	.002	3	6
CNS	RBKS →	-0.751	-1.103	.001	.001	3	5
STOMACH	TTLL12 →	+0.884	+0.936	.009	.005	3	4
BLOOD_Myeloma	ZDHHC11B →	+2.250	+1.917	<.001	<.001	3	4
OESOPHAGUS	COCH →	+3.162	+1.069	<.001	.002	3	4
LIVER	SAA1 →	-3.112	-1.008	.007	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,366 associations by consensus.

SOD1 vs TRIO — BLOOD_Lymphoma

Explore this scatter interactively →