SOCS7

Across TCGA patient cohorts, SOCS7 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,997 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SOCS7-associated proteins across cancer lineages are LIG3, DHX9, and NXF1. Each is linked with SOCS7 in more than 7 cancer types. Because this analysis shows association rather than direction, both SOCS7-to-partner and partner-to-SOCS7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOCS7 versus LIG3 in LSCC, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SOCS7→partner) and Y-score (partner→SOCS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LIG3 →	+0.533	+0.871	<.001	<.001	3	8
LSCC	DHX9 →	+0.281	+0.852	<.001	<.001	3	7
GBM	NXF1 →	+0.305	+0.464	<.001	.001	3	7
GBM	STAG2 →	+0.259	+0.452	.007	<.001	3	6
HNSC	TRIM21 →	-0.470	-0.533	<.001	<.001	3	6
LSCC	USP39 →	+0.367	+0.875	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,997 associations by consensus.

SOCS7 vs LIG3 — LSCC

Explore this scatter interactively →