suppressor of cytokine signaling 5 pseudogene 4Genealiases: []
Q-omics provides the consensus-scored SOCS5P4 profile across patient tissues and cancer cell-line models. SOCS5P4 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in LUAD. Among the 18 cancer types available for tumor–normal comparison, SOCS5P4 is differentially expressed in 12, with the highest sampling consensus in COAD. Additionally, SOCS5P4 RNA expression shows 19,132 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight LUAD, COAD, and UVM as cancer lineages where SOCS5P4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SOCS5P4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SOCS5P4 survival associations across molecular data types. SOCS5P4 RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SOCS5P4 RNA expression–survival associations across cancer types. High SOCS5P4 expression shows unfavorable associations in LUAD, KIRP, UVM, KIRC and KICH, but favorable associations in HNSC. The LUAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUAD as the clearest survival context for SOCS5P4 RNA expression.
This table summarizes SOCS5P4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for SOCS5P4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SOCS5P4 shows higher tumor expression in COAD, KIRP, KIRC, LUSC, HNSC and LUAD. The COAD box plot shows higher SOCS5P4 RNA expression in tumor versus normal tissue (log2 FC = +0.332, t-test p < 0.001).
This table shows molecular features associated with SOCS5P4 in patient tissues and cancer cell lines. In patient samples, SOCS5P4 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
