SOCS4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SOCS4 protein abundance is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SOCS4-associated genes across cancer lineages are LINC00316 and RPL7L1P13. Each is linked with SOCS4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SOCS4-to-partner and partner-to-SOCS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SOCS4 versus LINC00316 in GBM, with a Pearson correlation of -0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOCS4→partner) and Y-score (partner→SOCS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMLINC00316 →-0.245-0.361<.001.00631
GBMRPL7L1P13 →-0.187-0.717.001.00331
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SOCS4 vs LINC00316 — GBM

Per-sample scatter of SOCS4 vs LINC00316 in GBM (Pearson r = -0.73).

Explore this scatter interactively →

Exploration