SOAT2

Across TCGA cell cohorts, SOAT2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SOAT2-associated genes across cancer lineages are FOXI2, MYMK, and IQCF5. Each is linked with SOAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SOAT2-to-partner and partner-to-SOAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXI2 grouped by SOAT2-low versus SOAT2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SOAT2→partner) and Y-score (partner→SOAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	FOXI2 →	+0.006	+5.321	.004	.005	3	1
BLOOD_Leukemia	MYMK →	+0.031	+4.922	<.001	.009	3	1
BLOOD_Leukemia	IQCF5 →	+0.124	+5.201	<.001	.006	3	1
BLOOD_Leukemia	KRTAP5-4 →	+0.035	+4.922	<.001	.009	3	1
LARGE_INTESTINE	CFHR2 →	+0.046	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

FOXI2 by SOAT2 expression — CNS

Explore this box plot interactively →