SNX9

Across TCGA pan-cancer cohorts, SNX9 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SNX9 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SNX9 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNX9 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

LSCC, CCRCC, and PDAC are the cancer types where SNX9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.530	0.841	.002	42	view →
CCRCC	OS	Tertile	III,IV	0.884	0.543	.005	24	view →
PDAC	OS	Quartile	All	0.328	0.552	.022	6	view →
GBM	OS	Quartile	All	0.720	0.886	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SNX9–LSCC (DFS)

Open the LSCC breakdown →