SNX9

Across TCGA cell cohorts, SNX9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,956 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SNX9-associated GO terms across cancer lineages are Positive regulation of receptor localization to synapse, Regulation of membrane protein ectodomain proteolysis, and Positive regulation of focal adhesion assembly. Each is linked with SNX9 in more than 10 cancer types. Because this analysis shows association rather than direction, both SNX9-to-partner and partner-to-SNX9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of receptor localization to synapse grouped by SNX9-low versus SNX9-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX9→partner) and Y-score (partner→SNX9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of receptor localization to synapse →	+0.189	+0.794	<.001	<.001	3	11
OESOPHAGUS	Regulation of membrane protein ectodomain proteolysis →	+0.190	+1.616	.004	<.001	3	10
BONE	Positive regulation of focal adhesion assembly →	+0.277	+1.346	<.001	<.001	3	10
BONE	Actin filament bundle organization →	+0.116	+0.952	<.001	<.001	3	10
BONE	Actin filament organization →	+0.104	+1.058	<.001	<.001	3	10
BONE	Dephosphorylation →	+0.036	+0.858	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,956 associations by consensus.

Positive regulation of receptor localization to synapse by SNX9 expression — LUNG_NSCLC_LUSC

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