SNX9

Across TCGA cell cohorts, SNX9 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNX9-associated genes across cancer lineages are MMP27, CBLL2, and KRTAP12-3. Each is linked with SNX9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX9-to-partner and partner-to-SNX9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP27 grouped by SNX9-low versus SNX9-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX9→partner) and Y-score (partner→SNX9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MMP27 →	+0.026	+5.969	<.001	.001	3	1
BLOOD_Leukemia	CBLL2 →	+0.036	+5.201	<.001	.006	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.082	+5.539	<.001	.003	3	1
SKIN	UGT2B10 →	+0.006	+4.977	<.001	.007	3	1
SKIN	MGAT4D →	+0.023	+4.977	<.001	.007	3	1
LARGE_INTESTINE	MAGEB4 →	+0.014	+4.000	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MMP27 by SNX9 expression — BLOOD_Leukemia

Explore this box plot interactively →